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Article

Novel chemosensitive single-nucleotide polymorphism markers to targeted regimens in metastatic colorectal cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 2011

Kim Jin C, Kim Seon Y, Cho Dong H, Ha Ye J, Choi Eun Y, Kim Chan W, Roh Seon A, Kim Tae W, Ju Hyoungseok, Kim Yong S

Abstract excerpt

PURPOSE: Methods for predicting individual responsiveness to targeted chemotherapy are urgently needed, considering the frequent resistance and extremely high cost. EXPERIMENTAL DESIGN: A chemosensitive single-nucleotide polymorphism (SNP) discovery schema is presented that utilizes (i) genome-wide SNP screening with a human SNP array and an in vitro chemosensitivity assay in 118 colorectal cancers, (ii) clinical...

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Source

Identifiers

PMID: 21239504
DOI: 10.1158/1078-0432.CCR-10-1907

Genes

LIFR
ISX
ANXA11
LINS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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