Article
Selective carboxyl methylation of structurally altered calmodulins in Xenopus oocytes.
The Journal of biological chemistry - 5 Dec 1990
Desrosiers R R, Romanik E A, O'Connor C M
Abstract excerpt
The eucaryotic protein carboxyl methyltransferase specifically modifies atypical D-aspartyl and L-isoaspartyl residues which are generated spontaneously as proteins age. The selectivity of the enzyme for altered proteins in intact cells was explored by co-injecting Xenopus laevis oocytes with S-adenosyl-L-[methyl-3H]methionine and structurally altered calmodulins generated during a 14-day preincubation in vitro....
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