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Article

Selective carboxyl methylation of structurally altered calmodulins in Xenopus oocytes.

The Journal of biological chemistry - 5 Dec 1990

Desrosiers R R, Romanik E A, O'Connor C M

Abstract excerpt

The eucaryotic protein carboxyl methyltransferase specifically modifies atypical D-aspartyl and L-isoaspartyl residues which are generated spontaneously as proteins age. The selectivity of the enzyme for altered proteins in intact cells was explored by co-injecting Xenopus laevis oocytes with S-adenosyl-L-[methyl-3H]methionine and structurally altered calmodulins generated during a 14-day preincubation in vitro....

Topics

Animals
Brain
Calcium Chloride
Calmodulin
Cattle
Chickens
Edetic Acid
Escherichia coli
Female
Genetic Variation
Kinetics
Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oocytes

Recombinant Proteins

S-Adenosylmethionine

Sulfur Radioisotopes

Xenopus

Source

Identifiers

PMID: 2123492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2123492-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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