Article
Low abundance of sweat duct Cl- channel CFTR in both healthy and cystic fibrosis athletes with exceptionally salty sweat during exercise.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2011
Brown Mary Beth, Haack Karla K V, Pollack Brian P, Millard-Stafford Mindy, McCarty Nael A
Abstract excerpt
To understand potential mechanisms explaining interindividual variability observed in human sweat sodium concentration ([Na(+)]), we investigated the relationship among [Na(+)] of thermoregulatory sweat, plasma membrane expression of Na(+) and Cl(-) transport proteins in biopsied human eccrine sweat ducts, and basal levels of vasopressin (AVP) and aldosterone. Lower ductal luminal membrane expression of the Cl(-)...
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