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Article

Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder.

Acta paediatrica (Oslo, Norway : 1992) - 1 Jun 2011

Swerdloff Ronald S, Lue YanHe, Liu Peter Y, Erkkilä Krista, Wang Christina

Abstract excerpt

UNLABELLED: 41XXY mouse models share many characteristics of the human 47XXY Klinefelter syndrome (KS). This manuscript discusses the relative role of androgen deficiency and X chromosome genes resulting in the XXY mouse phenotype. The similarities in phenotype between 47XXY men and 41XXY mice suggest that the clinical manifestations in XXY men may be because of gene-dosage effect from genes that escape X...

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Identifiers

PMID: 21226760
DOI: 10.1111/j.1651-2227.2011.02149.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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