Article
No evidence of association between the LINGO4 gene and essential tremor in Chinese Han patients.
Parkinsonism & related disorders - 1 Mar 2012
Liang Hui, Zheng Wen, Xu Hongbo, Lei Jing, Song Zhi, Jiang Xuhong, Zeng Zeshuai, Deng Hao
Abstract excerpt
Essential tremor (ET) is shown an autosomal dominant mode of inheritance, with no disease-causing gene has been found. Genetic variations in the leucine-rich repeat and lg domain containing nogo receptor-interacting protein genes (LINGO1 and LINGO2) were reported to be associated with an increased risk of developing ET. To explore whether the LINGO4 gene (a homologous gene of the LINGO1 and the LINGO2 genes)...
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