Immunomodulatory characteristics of a novel antiproliferative protein, suppressin.

doi:10.1016/0165-5728(90)90102-s

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Article

Immunomodulatory characteristics of a novel antiproliferative protein, suppressin.

Journal of neuroimmunology - 1 Dec 1990

Carr D J, Blalock J E, Green M M, LeBoeuf R D

Abstract excerpt

We investigated the immunoregulatory properties of a recently described inhibitor of lymphocyte proliferation, suppressin (SPN). It was determined that preincubation of murine leukocytes with SPN enhances natural killer cell (NK) activity. In addition, SPN potentiates interferon-gamma (IFN-gamma)...

Topics

Animals
Female
Immunosuppressive Agents
Interferon-gamma
Killer Cells, Natural
Lymphocytes
Male
Mice
Mice, Inbred C57BL
Phenotype
Thymus Hormones

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