Article
Sugar-nucleotide donor specificity of histo-blood group A and B transferases is based on amino acid substitutions.
The Journal of biological chemistry - 5 Nov 1990
Yamamoto F, Hakomori S
Abstract excerpt
Four amino acid substitutions (aa 176, 235, 266, and 268) have been found between the coding regions of cDNAs for histo-blood group A and B transferases (Yamamoto F., Clausen, H., White, T., Marken, J., and Hakomori, S. (1990) Nature 345, 229-233). Here we establish the basis of differential affi...
Topics
- ABO Blood-Group System
- Amino Acid Sequence
- Base Sequence
- Carbohydrate Conformation
- Carbohydrate Sequence
- Chimera
- Cloning, Molecular
- Galactosyltransferases
- Genotype
- HeLa Cells
- Humans
- Introns
- Molecular Sequence Data
- N-Acetylgalactosaminyltransferases
- Oligonucleotide Probes
- Phenotype
- Restriction Mapping
- Sequence Homology, Nucleic Acid