Article
Human histo-blood group A2 transferase coded by A2 allele, one of the A subtypes, is characterized by a single base deletion in the coding sequence, which results in an additional domain at the carboxyl terminal.
Biochemical and biophysical research communications - 31 Aug 1992
Yamamoto F, McNeill P D, Hakomori S
Abstract excerpt
We have identified a possible mutation which characterizes A2 alleles (a minor subtype of A) at the human histo-blood group ABO locus based on polymerase chain reaction (PCR) of genomic DNA, followed by nucleotide sequencing of the amplified fragments. The A2 subtype has a single base deletion ne...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Chromosome Deletion
- DNA
- DNA, Recombinant
- Exons
- Fucosyl Galactose alpha-N-Acetylgalactosaminyltransferase
- HeLa Cells
- Humans
- Molecular Sequence Data