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Article

Genetic and functional linkage of Kir5.1 and Kir2.1 channel subunits

1 Mar 2001

Abstract excerpt

We have identified several cDNAs for the human Kir5.1 subunit of inwardly rectifying K(+) channels. Alternative splicing of exon 3 and the usage of two alternative polyadenylation sites contribute to cDNA diversity. The hKir5.1 gene KCNJ16 is assigned to chromosomal region 17q23.1-24.2, and is separated by only 34 kb from the hKir2.1 gene (KCNJ2). In the brain, Kir5.1 mRNA is restricted to the evolutionary older...

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PMID: 11240146
DOI: 10.1016/s0014-5793(01)02202-5

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