Article
Mitochondrial Biogenesis, Activity, and DNA Isolation in Chondrocytes.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Wang Yun, Chen Liang-Yu, Liu-Bryan Ru
Abstract excerpt
Chondrocytes, the only cells in articular cartilage, are metabolically active and responsible for the turnover of extracellular matrix and maintenance of the tissue homeostasis. Changes in chondrocyte function can cause degradation of the matrix and loss of articular cartilage integrity, leading to development and progression of osteoarthritis (OA). These changes are exemplified by accumulated mitochondrial...
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