Article
A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits.
Biological psychiatry - 1 May 2011
Stein Murray B, Yang Bao-Zhu, Chavira Denise A, Hitchcock Carla A, Sung Sharon C, Shipon-Blum Elisa, Gelernter Joel
Abstract excerpt
BACKGROUND: Selective mutism (SM), considered an early-onset variant of social anxiety disorder, shares features of impaired social interaction and communication with autism spectrum disorders (ASDs) suggesting a possible shared pathophysiology. We examined association of a susceptibility gene, contactin-associated protein-like 2 (CNTNAP2), for ASDs and specific language impairment with SM and social...
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