Article
A common variant of CNTNAP2 is associated with sub-threshold autistic traits and intellectual disability.
PloS one - 1 Jan 2021
Shiota Yuka, Hirosawa Tetsu, Yoshimura Yuko, Tanaka Sanae, Hasegawa Chiaki, Iwasaki Sumie, An Kyung-Min, Soma Daiki, Sano Masuhiko, Yokoyama Shigeru, Kikuchi Mitsuru
Abstract excerpt
Sub-threshold autistic traits are common in the general population. Children with sub-threshold autistic traits have difficulties with social adaptation. Contactin-associated protein-like 2 (CNTNAP2) is associated with the development of Autism spectrum disorder (ASD) and the single-nucleotide polymorphism rs2710102 (G/A) of CNTNAP2 is suggested to contribute to sub-threshold social impairments and intellectual...
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