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Article

Defining the contribution of CNTNAP2 to autism susceptibility.

PloS one - 1 Jan 2013

Sampath Srirangan, Bhat Shambu, Gupta Simone, O'Connor Ashley, West Andrew B, Arking Dan E, Chakravarti Aravinda

Abstract excerpt

Multiple lines of genetic evidence suggest a role for CNTNAP2 in autism. To assess its population impact we studied 2148 common single nucleotide polymorphisms (SNPs) using transmission disequilibrium test (TDT) across the entire ~3.3 Mb CNTNAP2 locus in 186 (408 trios) multiplex and 323 simplex families with autistic spectrum disorder (ASD). This analysis yielded two SNPs with nominal statistical significance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24147096
DOI: 10.1371/journal.pone.0077906
PMCID: PMC3798378

Genes

CNTNAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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