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Article

Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice.

The Journal of cell biology - 27 Dec 2010

Paul Pradyut K, Gupta Sanjay K, Bhatnagar Shephali, Panguluri Siva K, Darnay Bryant G, Choi Yongwon, Kumar Ashok

Abstract excerpt

Skeletal muscle wasting is a major human morbidity, and contributes to mortality in a variety of clinical settings, including denervation and cancer cachexia. In this study, we demonstrate that the expression level and autoubiquitination of tumor necrosis factor (α) receptor adaptor protein 6 (TR...

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Source

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Identifiers

PMID: 21187332
DOI: 10.1083/jcb.201006098
PMCID: PMC3010064

Genes

TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21187332-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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