Article
Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients.
Progress in neuro-psychopharmacology & biological psychiatry - 15 Feb 2008
Zhang Jing, Shen Yifeng, He Guang, Li Xingwang, Meng Junwei, Guo Shengzhen, Li Huafang, Gu Niufan, Feng Guoyin, He Lin
Abstract excerpt
BACKGROUND: Suicide is a significant health problem throughout the world. The serotoninergic system is believed to be involved in suicidal behavior and there is evidence of biological abnormalities of two serotonin receptors (HTR2A, HTR2C) and one serotonin transporter (5HTT) in suicide victims. Rs6313 (T102C) of HTR2A and rs6318 (Cys23Ser) of HTR2C have been investigated in suicide behavior in other studies....
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