Article
Carotid atherosclerotic markers in CADASIL.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2011
Mawet Jérôme, Vahedi Katayoun, Aout Mounir, Vicaut Eric, Duering Marco, Touboul Pierre Jean, Dichgans Martin, Chabriat Hugues
Abstract excerpt
PURPOSE: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a cerebral small vessel disease caused by mutations of the NOTCH3 gene. Marked variations in disease severity have raised the hypothesis that non-genetic factors may modulate the expressivity of the phenotype. The aim of the current study was to evaluate whether atherosclerosis, assessed by carotid...
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