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Article

Identifying cancer driver genes in tumor genome sequencing studies.

Bioinformatics (Oxford, England) - 15 Jan 2011

Youn Ahrim, Simon Richard

Abstract excerpt

MOTIVATION: Major tumor sequencing projects have been conducted in the past few years to identify genes that contain 'driver' somatic mutations in tumor samples. These genes have been defined as those for which the non-silent mutation rate is significantly greater than a background mutation rate...

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Identifiers

PMID: 21169372
DOI: 10.1093/bioinformatics/btq630
PMCID: PMC3018819

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21169372-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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