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Article

Anti-Group A Streptococcal Vaccine Epitope

18 Dec 2010

Abstract excerpt

Streptococcus pyogenes infections remain a health problem in several countries due to poststreptococcal sequelae. We developed a vaccine epitope (StreptInCor) composed of 55 amino acids residues of the C-terminal portion of the M protein that encompasses both T and B cell protective epitopes. The nuclear magnetic resonance (NMR) structure of the StreptInCor peptide showed that the structure was composed of two...

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PMID: 21169359
DOI: 10.1074/jbc.m110.132118

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