Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

StreptInCor: A Candidate Vaccine Epitope against S. pyogenes Infections Induces Protection in Outbred Mice

8 Apr 2013

Abstract excerpt

Infection with Streptococcus pyogenes (S. pyogenes) can result in several diseases, particularly in children. S. pyogenes M protein is the major virulence factor, and certain regions of its N-terminus can trigger autoimmune sequelae such as rheumatic fever in susceptible individuals with untreated group A streptococcal pharyngitis. In a previous study, we utilized a large panel of human peripheral blood cells to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Streptococcal Infections and Treatments
Share to Toxin Mechanisms and Immunotoxins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23593359
DOI: 10.1371/journal.pone.0060969

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

StreptInCor: A Candidate Vaccine Epitope against S. pyogenes Infections Induces Protection in Outbred MicePMID 23593359Read ↗

Anti-Group A Streptococcal Vaccine EpitopeSemantic proximity Read ↗

Strategic development of the conserved region of the M protein and other candidates as vaccines to prevent infection with group A streptococciSemantic proximity Read ↗

Streptococcus pyogenes strains in Sao Paulo, Brazil: molecular characterization as a basis for StreptInCor coverage capacity analysis.Semantic proximity Read ↗

Novel Conserved Group A Streptococcal Proteins Identified by the Antigenome Technology as Vaccine Candidates for a Non-M Protein-Based VaccineSemantic proximity Read ↗

HLA class II transgenic mice develop a safe and long lasting immune response against StreptInCor, an anti-group A streptococcus vaccine candidateSemantic proximity Read ↗

Streptococcal superantigens and the return of scarlet feverSemantic proximity Read ↗

Molecular biology of Group A Streptococcus and its implications in vaccine strategies.Semantic proximity Read ↗

Targeted Amino Acid Substitutions Impair Streptolysin O Toxicity and Group A <i>Streptococcus</i> VirulenceSemantic proximity Read ↗

Combinatorial Synthetic Peptide Vaccine Strategy Protects against Hypervirulent CovR/S Mutant StreptococciSemantic proximity Read ↗

Streptococcus pyogenes: Insight into the function of the streptococcal superantigensSemantic proximity Read ↗

A Lipid Core Peptide Construct Containing a Conserved Region Determinant of the Group A Streptococcal M Protein Elicits Heterologous Opsonic AntibodiesSemantic proximity Read ↗

Reverse and structural vaccinology approach to design a highly immunogenic multi-epitope subunit vaccine against Streptococcus pneumoniae infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.