Contribution of cryptic epitopes in designing a group A streptococcal vaccine.

doi:10.1080/21645515.2018.1462427

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Article

Contribution of cryptic epitopes in designing a group A streptococcal vaccine.

Human vaccines & immunotherapeutics - 1 Jan 2018

Ozberk Victoria, Pandey Manisha, Good Michael F

Abstract excerpt

A successful vaccine needs to target multiple strains of an organism. Streptococcus pyogenes is an organism that utilizes antigenic strain variation as a successful defence mechanism to circumvent the host immune response. Despite numerous efforts, there is currently no vaccine available for this organism. Here we review and discuss the significant obstacles to vaccine development, with a focus on how cryptic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29873591
DOI: 10.1080/21645515.2018.1462427
PMCID: PMC6150013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.