Article
Role of somatic mutation in atherosclerosis.
Progress in clinical and biological research - 1 Jan 1990
Penn A
Abstract excerpt
Thus, plaque DNAs from two widely different classes of organisms exhibit similar molecular alterations, which are comparable to those previously described for a number of tumor DNAs. These findings represent the first direct demonstration that mutational events may be critical in the etiology of arteriosclerotic plaques.
Topics
- Animals
- Arteriosclerosis
- Carcinogens
- Clone Cells
- Humans
- Muscle, Smooth
- Mutation
- Neoplasms, Experimental
- Transfection
- Viruses