Article
Environmental carcinogens and mutational pathways in atherosclerosis.
International journal of hygiene and environmental health - 1 May 2015
Pulliero A, Godschalk R, Andreassi M G, Curfs D, Van Schooten F J, Izzotti A
Abstract excerpt
Atherosclerosis is associated with DNA damage in both circulating and vessel-wall cells and DNA adducts derived from exposure to environmental mutagens are abundant in atherosclerotic vessels. Environmental chemical carcinogens identified as risk factor for atherosclerosis include polycyclic aromatic hydrocarbons (benzo(a)pyrene, dimethylbenz(a)anthracene, beta-naphthoflavone, pyrene, 3-methylcolanthrene),...
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