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Article

CTLA4 A49G polymorphism shows significant association with glioma risk in a Chinese population.

Biochemical genetics - 1 Apr 2011

Wu Qihan, Zhan Xiaoying, Dou Tonghai, Chen Hongyan, Fan Weiwei, Zhou Keke, Zhang Haishi, Zheng Hongxia, Cai Yanyan, Zhao Yao, Huang Fengping, Zhou Liangfu, Mao Ying, Lu Daru

Abstract excerpt

Cytotoxic T lymphocyte-associated antigen-4 (CTLA4) A49G is a polymorphism that is extensively studied in various cancers. To investigate whether it is associated with the occurrence of glioma in Chinese patients, we performed a case-control research study with 670 patients and 680 controls. In this group, we found that the genotype at this locus is significantly associated with glioma risk (GG vs. AA: P = 0.045;...

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Source

Identifiers

PMID: 21165767
DOI: 10.1007/s10528-010-9398-0

Genes

CTLA4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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