Article
Transforming growth factor-β1 29T>C genetic polymorphism is associated with lymph node metastasis in patients with adenocarcinoma of the lung.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Oct 2010
Minamiya Yoshihiro, Miura Masatomo, Hinai Yudai, Saito Hajime, Ito Manabu, Ono Takashi, Toda Hiroshi, Motoyama Satoru, Ogawa Jun-ichi
Abstract excerpt
Transforming growth factor-β1 (TGF-β1) is known to suppress antitumor immune responses, and its overexpression is closely associated with a poor prognosis in patients with malignant tumors. Moreover, TGF-β1 29T>C genetic polymorphism is known to affect survival among breast cancer patients. The relationship between TGF-β1 polymorphism and the clinicopathological characteristics of non-small cell lung cancer...
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