Article
Mycobacterium leprae: genes, pseudogenes and genetic diversity.
Future microbiology - 1 Jan 2011
Singh Pushpendra, Cole Stewart T
Abstract excerpt
Leprosy, which has afflicted human populations for millenia, results from infection with Mycobacterium leprae, an unculturable pathogen with an exceptionally long generation time. Considerable insight into the biology and drug resistance of the leprosy bacillus has been obtained from genomics. M. leprae has undergone reductive evolution and pseudogenes now occupy half of its genome. Comparative genomics of four...
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