Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the Q223R polymorphism with age at menarche in the leptin receptor gene in humans.

Biology of reproduction - 1 Apr 2011

Riestra P, Garcia-Anguita A, Torres-Cantero A, Bayonas M J, de Oya M, Garces C

Abstract excerpt

Although genetics clearly influences the onset of menarche, the association of age at menarche (AAM) with variants in genes related to energy homeostasis remains unexplored. Our aim was to analyze the relationship of the Q223R polymorphism in the leptin receptor gene (LEPR(Q223R)) with AAM in a p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Amino Acid Substitution
Share to Cross-Sectional Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Association Studies

Share to Menarche

Share to Receptors, Leptin

Source

Identifiers

PMID: 21159927
DOI: 10.1095/biolreprod.110.088500

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21159927-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the Q223R polymorphism with age at menarche in the leptin receptor gene in humans.PMID 21159927Read ↗

The LEP G-2548A gene polymorphism is associated with age at menarche and breast cancer susceptibility.Semantic proximity Read ↗

Polymorphisms in adiposity-related genes are associated with age at menarche and menopause in breast cancer patients and healthy women.Semantic proximity Read ↗

Sex-specific association between leptin receptor polymorphisms and leptin levels and BMI in healthy adolescents.Semantic proximity Read ↗

Three common variants of LEP, NPY1R and GPR54 show no association with age at menarche.Semantic proximity Read ↗

The LEP gene and age of menarche: maternal age as a potential cause of hidden stratification in association studies.Semantic proximity Read ↗

The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche.Semantic proximity Read ↗

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.Semantic proximity Read ↗

Influence of the leptin G-2548A polymorphism on leptin levels and anthropometric measurements in healthy Spanish adolescents.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms Pvu II and Xba I influence association between leptin receptor gene polymorphism (Gln223Arg) and bone mineral density in young men.Semantic proximity Read ↗

Associations of progesterone receptor polymorphisms with age at menarche and menstrual cycle length.Semantic proximity Read ↗

Vitamin D receptor (VDR) gene polymorphisms and age onset in type 1 diabetes mellitus.Semantic proximity Read ↗

Lack of association between the ESR1 rs9340799 polymorphism and age at menarche: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.