Article
The t(6;9)(p22;q34) in myeloid neoplasms: a retrospective study of 16 cases.
Cancer genetics and cytogenetics - 1 Dec 2010
Gupta Monika, Ashok Kumar J, Sitaram Usha, Neeraj S, Nancy A, Balasubramanian Poonkuzhali, Abraham Aby, Mathews Vikram, Viswabandya Auro, George Biju, Chandy Mammen, Srivastava Alok, Srivastava Vivi M
Abstract excerpt
Among patients with acute myeloid leukemia (AML), the t(6;9) (p22;q34) is a rare but defined subset with a poor prognosis. We report 16 patients with the t(6;9), of whom 13 had AML, 2 had myelodysplastic syndrome (MDS), and 1 had chronic myeloid leukemia in myeloid blast crisis (CML-BC). All except for one were evaluated at diagnosis. The median age was 34.5 (range: 7-62 years), with 12 adults and 12 males....
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