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Article

Clinicopathologic and molecular characterization of myeloid neoplasms with isolated t(6;9)(p23;q34).

International journal of laboratory hematology - 1 Aug 2017

Visconte V, Shetty S, Przychodzen B, Hirsch C, Bodo J, Maciejewski J P, Hsi E D, Rogers H J

Abstract excerpt

INTRODUCTION: The t(6;9)(p23;q34);DEK-NUP214 [t(6;9)] abnormality is found in 0.7-1.8% of patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). FLT3-ITD mutations are detected in t(6;9) patients. The t(6;9) abnormality is associated with poor outcomes. We studied the clinicopathologic and molecular profiles of patients with AML/MDS carrying t(6;9). METHODS: We collected clinical data of...

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Identifiers

PMID: 28318095
DOI: 10.1111/ijlh.12641
PMCID: PMC8404557

Genes

FLT3
DEK
STAT3

Provenance

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