Article
[Determinants of resistance to chlortetracycline and other antibiotics in chlortetracycline-producing strain of Streptomyces aureofaciens].
Genetika - 1 Apr 1990
Chinenova T A, Biriukova I V, Voeĭkova T A, Emel'ianova L K, Klochkova O A, Sezonov G V, Lomovskaia N D
Abstract excerpt
Data are presented on resistance of Streptomyces aureofaciens strain TB-633 FU--the producer of chlortetracycline (CTC) to autogenous antibiotics and a number of other antibiotics. It is demonstrated that resistance to CTC is specified by ctr genes of constitutive expression as well as by inducible genes. CTC and ethidium bromide may serve as efficient inductors of inducible ctr genes. The induction process is...
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