Article
[Amplifying sequences in the Streptomyces coelicolor A3 (2) gene].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Dec 1990
Zavorotnaia S A, Fedorenko V A, Starodubtseva L I, Danilenko V N
Abstract excerpt
The unstable feature of ristomycin resistance in S. coelicolor A3 (2) was studied. It was shown that the frequency of ristomycin-resistant derivatives was high in both chloramphenicol sensitive mutants and their resistant revertants. The 15- and 20-kb DNA sequences capable of amplifying were detected in the chloramphenicol resistant revertants. In the genomes of the studied strains they were represented by 50 and...
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