Article
DNA methyltransferase 3B gene increases risk of early onset schizophrenia.
Neuroscience letters - 25 Oct 2009
Zhang Chen, Fang Yiru, Xie Bin, Cheng Wenhong, Du Yasong, Wang Dongxiang, Yu Shunying
Abstract excerpt
OBJECTIVE: Consistent evidence indicated that aberrant DNA methylation may be involved in the development of schizophrenia. DNA methyltransferase 3B (DNMT3B) is the key methyltransferase in DNA methylation regulations. In this study, we investigated the association between DNMT3B polymorphisms and the susceptibility of early onset schizophrenia in Chinese Han population. METHODS: Case-control (patients=381 and...
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