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Article

The interaction of RELN-DNMT genes involving in neurotrophin signaling pathway contributes to schizophrenia susceptibility.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Apr 2024

Ping Junjiao, Wan Jing, Luo Jiali, Du Baoguo, Liu Xinxia, Jiang Tingyun, Zhang Jie

Abstract excerpt

OBJECTIVE: Schizophrenia belongs to a severe mental illness with complicated clinical presentations, an ill-defined pathogenesis, and no known cause. Many genetic studies imply that polygenic interaction is important in the development of schizophrenia. The main mechanism of the RELN-BDNF-CREB-DNMT signaling pathway in neurodevelopment involves RELN, brain-derived neurotrophic factor (BDNF), transcription factor...

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Source

Identifiers

PMID: 38296839
DOI: 10.1002/jdn.10316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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