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Article

Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.

PloS one - 2 Dec 2010

Jonsson Ing-Marie, Juuti Jarmo T, François Patrice, AlMajidi Rana, Pietiäinen Milla, Girard Myriam, Lindholm Catharina, Saller Manfred J, Driessen Arnold J M, Kuusela Pentti, Bokarewa Maria, Schrenzel Jacques, Kontinen Vesa P

Abstract excerpt

BACKGROUND: Ecs is an ATP-binding cassette (ABC) transporter present in aerobic and facultative anaerobic gram-positive Firmicutes. Inactivation of Bacillus subtilis Ecs causes pleiotropic changes in the bacterial phenotype including inhibition of intramembrane proteolysis. The molecule(s) transp...

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Identifiers

PMID: 21151985
DOI: 10.1371/journal.pone.0014209
PMCID: PMC2996298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21151985-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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