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The Type VII Secretion System ofStaphylococcus

3 Aug 2021

Abstract excerpt

The type VII protein secretion system (T7SS) of Staphylococcus aureus is encoded at the ess locus. T7 substrate recognition and protein transport are mediated by EssC, a membrane-bound multidomain ATPase. Four EssC sequence variants have been identified across S. aureus strains, each accompanied by a specific suite of substrate proteins. The ess genes are upregulated during persistent infection, and the secretion...

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PMID: 34343022
DOI: 10.1146/annurev-micro-012721-123600

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