Back to search

Article

Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiome

2024-01-23

Abstract excerpt

Arms races between mobile genetic elements and prokaryotic hosts are major drivers of ecological and evolutionary change in microbial communities. Prokaryotic defense systems such as CRISPR-Cas have the potential to regulate microbiome composition by modifying the interactions among bacteria, plasmids, and phages. Here, we used longitudinal metagenomic data from 130 healthy and diseased individuals to study how th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fcfee108-6669-5123-a9a3-36d7cbdd8369
DOI
10.1101/2024.01.23.576851
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dynamics of CRISPR-mediated virus-host interactions in the human gut microbiomeDOI 10.1101/2024.01.23.576851
CRISPR-Cas immune repertoires as an ecological record of bacterial interactions with mobile genetic elements in the human gutSemantic proximity
Insights into the Human Virome Using CRISPR Spacers from MicrobiomesSemantic proximity
CRISPRs are associated with bacterial expansion in the human gut during the first year of lifeSemantic proximity
Diverse CRISPRs Evolving in Human MicrobiomesSemantic proximity
Extensive gut virome variation and its associations with host and environmental factors in a population-level cohortSemantic proximity
Extensive gut virome variation and its associations with host and environmental factors in a population-level cohortSemantic proximity
Ecological drivers of CRISPR immune systemsSemantic proximity
The gut virome and human health: From diversity to personalized medicineSemantic proximity
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome.Semantic proximity
Discovering Broader Host Ranges and an IS-bound Prophage Class Through Long-Read MetagenomicsSemantic proximity
Thousands of previously unknown phages discovered in whole-community human gut metagenomesSemantic proximity
Thousands of previously unknown phages discovered in whole-community human gut metagenomesSemantic proximity
Select a neighboring publication to make it the new centre.