Article
Are serum α- and β-carotene concentrations associated with the development of advanced beta-cell autoimmunity in children with increased genetic susceptibility to type 1 diabetes?
Diabetes & metabolism - 1 Apr 2011
Prasad M, Takkinen H-M, Nevalainen J, Ovaskainen M-L, Alfthan G, Uusitalo L, Kenward M G, Veijola R, Simell O, Ilonen J, Knip M, Virtanen S M
Abstract excerpt
AIM: Reactive oxygen intermediates have been implicated in mediating the destruction of insulin-producing beta cells and antioxidant nutrients thought to protect against such a process. This study aimed to assess the associations between serum α- and β-carotene concentrations, and the risk of advanced beta-cell autoimmunity, in children with HLA-conferred susceptibility to type 1 diabetes. METHODS: This...
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