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Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Jan 2011

Horibata Katsuyoshi, Saijo Masafumi, Bay Mui N, Lan Li, Kuraoka Isao, Brooks Philip J, Honma Masamitsu, Nohmi Takehiko, Yasui Akira, Tanaka Kiyoji

Abstract excerpt

Two UV-sensitive syndrome patients who have mild photosensitivity without detectable somatic abnormalities lack detectable Cockayne syndrome group B (CSB) protein because of a homozygous null mutation in the CSB gene. In contrast, mutant CSB proteins are produced in CS-B patients with the severe...

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Identifiers

PMID: 21143350
DOI: 10.1111/j.1365-2443.2010.01467.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21143350-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.PMID 21143350Read ↗

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