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Article

Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina.

Molecular vision - 18 Nov 2010

Mirza Saima, Plafker Kendra S, Aston Christopher, Plafker Scott M

Abstract excerpt

PURPOSE: Mounting evidence implicates chronic oxidative stress as a significant pathogenic factor in the development and progression of retinopathies, including age-related macular degeneration (AMD). The age-dependent toxic accumulation of oxidatively damaged proteins, lipids, and DNA in susceptible cells of the retina arises, at least in part, from a decreased capacity to eliminate these damaged biomolecules....

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PMID: 21139979
PMCID: PMC2994761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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