Article
Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina.
Molecular vision - 18 Nov 2010
Mirza Saima, Plafker Kendra S, Aston Christopher, Plafker Scott M
Abstract excerpt
PURPOSE: Mounting evidence implicates chronic oxidative stress as a significant pathogenic factor in the development and progression of retinopathies, including age-related macular degeneration (AMD). The age-dependent toxic accumulation of oxidatively damaged proteins, lipids, and DNA in suscept...
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