Article
A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.
Endocrine-related cancer - 1 Feb 2011
Walsh Kyle M, Choi Murim, Oberg Kjell, Kulke Matthew H, Yao James C, Wu Chengqing, Jurkiewicz Magdalena, Hsu Ling-I, Hooshmand Susanne M, Hassan Manal, Janson Eva T, Cunningham Janet L, Vosburgh Evan, Sackler Richard S, Lifton Richard P, Dewan Andrew T, Hoh Josephine
Abstract excerpt
Genetic studies of midgut carcinoid cancer have exclusively focused on genomic changes of the tumor cells. We investigated the role of constitutional genetic polymorphisms in predisposing individuals to ileal carcinoids. In all, 239 cases and 110 controls were collected from three institutions: t...
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