Article
Molecular characterization of 103 ovarian serous and mucinous tumors.
Pathology oncology research : POR - 1 Sept 2011
Vereczkey Ildikó, Serester Orsolya, Dobos Judit, Gallai Mónika, Szakács Orsolya, Szentirmay Zoltán, Tóth Erika
Abstract excerpt
The pathogenesis of ovarian carcinomas is heterogeneous, with even the same entities showing great variance. In our study we investigated the mutations of the BRAF, KRAS, and p53 genes in serous and mucinous borderline tumors and in low grade and high grade serous and mucinous tumors. The mutations of BRAF and KRAS genes have been shown in 60% of borderline and low grade (well differentiated) serous and mucinous...
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