Article
[Molecular carcinogenesis of ovarian carcinoma].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2005
Diebold J
Abstract excerpt
Correlating histological phenotype and molecular pathology epithelial ovarian tumours can be classified into a number of subgroups. High grade serous and endometrioid carcinomas are characterized by chromosomal instability which is due to functional loss of BRCA1/2 and TP53 mutations. The pattern of molecular aberrations of carcinosarcomas (Malignant müllerian mixed tumours) is similar to high grade serous...
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