Article
Inducible production of macrophage colony-stimulating factor (CSF-1) by malignant and normal human T cells.
Leukemia - 1 Jun 1990
Praloran V, Gascan H, Papin S, Chevalier S, Trossaërt M, Boursier M C
Abstract excerpt
The CEM-ON malignant T cell line and long-term cultured normal T cells can be induced to release CSF-1 in their culture supernatants. Chemical inducers (PMA + A23187) and, more interestingly, cytokines (tumor necrosis factor alpha (TNF alpha) and interleukin-1 alpha (IL-1 alpha)), as well as physiological (antigen + IL-2) or specific (anti-CD3 + IL-2 or PMA) stimuli, lead to rapid transient colony-stimulating...
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