Article
Macrophage activation for the production of immunostimulatory cytokines by delivering interleukin 1 via biodegradable microspheres.
Cytokine - 1 Nov 2000
Mullerad J, Cohen S, Voronov E, Apte R N
Abstract excerpt
Interleukin 1alpha (IL-1alpha), a pleiotropic cytokine with multiple anti-tumour activities, has been investigated in our laboratory for its potential to serve as an immunotherapeutic agent. In the present study, an attempt was made to direct IL-1alpha to macrophages, in order to induce their immunoregulatory activities. For that purpose, IL-1alpha was encapsulated within biodegradable poly(lactic/glycolic acid)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.