Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phylogenomic analysis of the uracil-DNA glycosylase superfamily.

Molecular biology and evolution - 1 Mar 2011

Lucas-Lledó J Ignacio, Maddamsetti Rohan, Lynch Michael

Abstract excerpt

The spontaneous deamination of cytosine produces uracil mispaired with guanine in DNA, which will produce a mutation, unless repaired. In all domains of life, uracil-DNA glycosylases (UDGs) are responsible for the elimination of uracil from DNA. Thus, UDGs contribute to the integrity of the genetic information and their loss results in mutator phenotypes. We are interested in understanding the role of UDG genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to Base Composition
Share to DNA, Intergenic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to Protein Isoforms

Share to Sequence Deletion

Share to Uracil

Share to Uracil-DNA Glycosidase

Source

Open in PubMed Open full text

Identifiers

PMID: 21135150
DOI: 10.1093/molbev/msq318
PMCID: PMC3107667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phylogenomic analysis of the uracil-DNA glycosylase superfamily.PMID 21135150Read ↗

On the molecular mechanism of GC content variation among eubacterial genomes.Semantic proximity Read ↗

Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria.Semantic proximity Read ↗

GC content variability of eubacteria is governed by the pol III alpha subunit.Semantic proximity Read ↗

SMUG2 DNA glycosylase from Pedobacter heparinus as a new subfamily of the UDG superfamily.Semantic proximity Read ↗

The underlying mechanisms of genetic innovation and speciation in the family Corynebacteriaceae: A phylogenomics approach.Semantic proximity Read ↗

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment.Semantic proximity Read ↗

Determinants of spontaneous mutation in the bacterium Escherichia coli as revealed by whole-genome sequencing.Semantic proximity Read ↗

The Rate and Molecular Spectrum of Spontaneous Mutations in the GC-Rich Multichromosome Genome of Burkholderia cenocepacia.Semantic proximity Read ↗

GC-content evolution in bacterial genomes: the biased gene conversion hypothesis expandsSemantic proximity Read ↗

Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis.Semantic proximity Read ↗

Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity.Semantic proximity Read ↗

The rate and molecular spectrum of spontaneous mutations in the GC-rich multi-chromosome genome of <i>Burkholderia cenocepacia</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.