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Genomic Legacies of Ancient Adaptation Illuminate GC-Content Evolution in Bacteria.

Microbiology spectrum - 14 Feb 2023

Teng Wenkai, Liao Bin, Chen Mengyun, Shu Wensheng

Abstract excerpt

Bacterial evolution is characterized by strong purifying selection as well as rapid adaptive evolution in changing environments. In this context, the genomic GC content (genomic GC) varies greatly but presents some level of phylogenetic stability, making it challenging to explain based on current hypotheses. To illuminate the evolutionary mechanisms of the genomic GC, we analyzed the base composition and...

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PMID: 36511682
DOI: 10.1128/spectrum.02145-22
PMCID: PMC9927291

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