Article
A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle aspiration biopsy.
Surgery - 1 Dec 2010
Mathur Aarti, Weng Julie, Moses Willieford, Steinberg Seth M, Rahbari Reza, Rahabari Reza, Kitano Mio, Khanafshar Elham, Ljung Britt-Marie, Duh Quan-Yang, Clark Orlo H, Kebebew Electron
Abstract excerpt
BACKGROUND: Approximately 30% of fine needle aspiration biopsies of the thyroid have inconclusive results. We conducted a prospective trial to determine whether clinical and molecular markers could be used in combination to improve the accuracy of thyroid fine needle aspiration biopsy. METHODS: Clinical, tumor genotyping for common somatic mutations (BRAF V600E, NRAS, KRAS, RET/PTC1, RET/PTC3, and NTRK1), and the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.