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Article

The combination of four molecular markers improves thyroid cancer cytologic diagnosis and patient management.

BMC cancer - 19 Nov 2015

Panebianco Federica, Mazzanti Chiara, Tomei Sara, Aretini Paolo, Franceschi Sara, Lessi Francesca, Di Coscio Giancarlo, Bevilacqua Generoso, Marchetti Ivo

Abstract excerpt

BACKGROUND: Papillary thyroid cancer is the most common endocrine malignancy. The most sensitive and specific diagnostic tool for thyroid nodule diagnosis is fine-needle aspiration (FNA) biopsy with cytological evaluation. Nevertheless, FNA biopsy is not always decisive leading to "indeterminate" or "suspicious" diagnoses in 10%-30% of cases. BRAF V600E detection is currently used as molecular test to improve the...

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Identifiers

PMID: 26581891
DOI: 10.1186/s12885-015-1917-2
PMCID: PMC4652365

Genes

BRAF
KIT

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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