Article
Molecular testing for somatic mutations improves the accuracy of thyroid fine-needle aspiration biopsy.
World journal of surgery - 1 Nov 2010
Moses Willieford, Weng Julie, Sansano Ileana, Peng Miao, Khanafshar Elham, Ljung Britt-Marie, Duh Quan-Yang, Clark Orlo H, Kebebew Electron
Abstract excerpt
BACKGROUND: Thyroid fine-needle aspiration (FNA) biopsy is indeterminate or suspicious in up to 30% of cases and these patients are commonly subjected to at least a diagnostic hemithyroidectomy. If malignant on histology, a completion thyroidectomy is usually performed, which may be associated with higher morbidity. To determine the clinical utility of genetic testing in thyroid FNA biopsy, we conducted a...
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