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Article

Indeterminate Single Thyroid Nodule: Synergistic Impact of Mutational Markers and Sonographic Features in Triaging Patients to Appropriate Surgery.

Thyroid : official journal of the American Thyroid Association - 1 Mar 2016

De Napoli Luigi, Bakkar Sohail, Ambrosini Carlo Enrico, Materazzi Gabriele, Proietti Agnese, Macerola Elisabetta, Basolo Fulvio, Miccoli Paolo

Abstract excerpt

BACKGROUND: Patients labeled as having indeterminate thyroid nodular disease following fine-needle aspiration cytology are at risk of non-optimal initial surgery: an overly radical total thyroidectomy, or an unnecessary two-stage operation. The objective of this study was to assess the impact of combining mutational markers and ultrasonographic (US) features preoperatively on predicting the risk of malignancy in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26548748
DOI: 10.1089/thy.2015.0311

Genes

NRAS
BRAF

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