Article
Voltage-dependent anion channel involved in the mitochondrial calcium cycle of cell lines carrying the mitochondrial DNA A4263G mutation.
Biochemical and biophysical research communications - 7 Jan 2011
Liu Yuqi, Gao Lei, Xue Qiao, Li Zongbin, Wang Lin, Chen Rui, Liu Mohan, Wen Yi, Guan Minxin, Li Yang, Wang Shiwen
Abstract excerpt
In this study, we investigated the effects of the voltage-dependent anion channel (VDAC) on the mitochondrial calcium cycle in cell lines carrying the mitochondrial DNA A4263G mutation. We established lymphoblastoid cell lines from three symptomatic individuals and one asymptomatic individual from the large Chinese Han family carrying the A4263G mutation; these were compared with three control cell lines. The...
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